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ABNORMAL HB STUDIES (HB ELECTROPHORESIS)

1400

Sample Type :

Blood

Report Delivery :

Same Day

Pre-test Information :

No special preparation is required for the test.

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Test(s) Included (0)

ABNORMAL HB STUDIES (HB ELECTROPHORESIS) (19)

  • FETAL HEMOGLOBIN (HbF)
  • HEMOGLOBIN A (HbA)
  • HEMOGLOBIN A2 (HbA2)
  • HEMOGLOBIN C (HbC)
  • HEMOGLOBIN D (HbD)
  • HEMOGLOBIN S (HbS)
  • HEMOGLOBIN E (HbE)
  • P2 WINDOW
  • P3 WINDOW
  • OTHERS
  • HAEMOGLOBIN
  • RBC COUNT
  • PCV
  • MCH
  • MCHC
  • MCV
  • R.D.W
  • PERIPHERAL SMEAR FINDING
  • INTERPRETATION

Item Description

haemoglobin is the protein p IgMent in the RBCs which is responsible for transporting oxygen to the tissues and organs. Genetic mutations can cause the body to produce abnormalities in the haemoglobin and hence, the abnormal haemoglobin can cause too little oxygen to reach your tissues and organs. A haemoglobin electrophoresis test is a blood test used to measure and identify the various kinds of haemoglobin in the bloodstream.

Important Information

1. HbA2 and HbF levels should be considered in conjunction with family history plus laboratory data including serum iron TIBC ferritin, red cell morphology, hemoglobin Hct and MCV 2. Blood transfusions may temporarily obscure or dilute abnormal Hb. If there is a history of blood transfusion, repeat testing after 3 months from the last date of transfusion is recommended 3. Quantitation of hemoglobins is performed optimally after 1 year of age 4. Mild to moderate increase in fetal hemoglobin can be seen in some acquired conditions such as pregnancy, megaloblastic anaemia, thyrotoxicosis, chronic kidney disease medications etc 5. P2 window above 10% is suggestive of either glycated hemoglobin or a possibility of an abnormal hemoglobin variant requiring further DNA studies for confirmation 6. P3 window above 10% is suggestive of either denatured forms of hemoglobin or a possibility of an abnormal hemoglobin variant a repeat analysis with a fresh sample is advised 7. This test detects Beta thalassemia and hemoglobinopathies. DNA analysis is recommended to rule out alpha thalassemia and silent carriers

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