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Anti-GBM Antibody (IF Method) Test

The glomerular basement membrane in the kidneys helps in the filtration of waste products. The antibodies that are produced against this membrane are known as the anti-glomerular basement membrane antibodies. These antibodies induce kidney damage by attacking the capillaries in the glomerular basement membrane. When this happens, the functioning of the kidneys gets affected owing to which proteins and blood leak into the urine. Anti-GBM antibodies target the basement membrane of the lungs and damage the lungs as well. The test measures anti-GBM antibodies in the blood.


Why is the test performed?

The test may be helpful in the assessment of individuals with rapid onset of pulmonary haemorrhage or renal failure. The test may also be used as a diagnostic aid for Goodpasture syndrome.

When is the test recommended?

The test may be recommended if the patient shows the signs and symptoms that are suggestive of kidney disease (Glomerulonephritis) or kidney and lung disease (Goodpasture syndrome). Such symptoms may include:
  • Kidney failure
  • Respiratory failure
  • Chest pain
  • Chills and fever
  • Weight loss
  • Hematuria
  • Vomiting
  • Pulmonary haemorrhage (coughing up blood)
  • Anaemia due to bleeding.
  • How is the sample collected?

    Venous blood is collected from a vein in the arm.

    How to prepare for the test?

    No special preparations are required for this test.

    Medically reviewed by Apollo Diagnostics

    Clinical information verified by our diagnostics team

    Also known as

    Anti-GBM Antibody (IF Method) Test

    Sample type

    As advised

    Gender

    Male & Female

    Age group

    All age groups

    Fasting required

    As advised

    Report delivery

    Speak to our care team

    Parameters

    Test specific

    APOLLO DIAGNOSTICS

    Anti-GBM Antibody (IF Method) Test

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    Reference ranges in report
    Doctor-ready digital report

    The glomerular basement membrane in the kidneys helps in the filtration of waste products. The antibodies that are produced against this membrane are known as the anti-glomerular basement membrane antibodies. These antibodies induce kidney damage by attacking the capillaries in the glomerular basement membrane. When this happens, the functioning of the kidneys gets affected owing to which proteins and blood leak into the urine. Anti-GBM antibodies target the basement membrane of the lungs and damage the lungs as well. The test measures anti-GBM antibodies in the blood.


    Why is the test performed?

    The test may be helpful in the assessment of individuals with rapid onset of pulmonary haemorrhage or renal failure. The test may also be used as a diagnostic aid for Goodpasture syndrome.

    When is the test recommended?

    The test may be recommended if the patient shows the signs and symptoms that are suggestive of kidney disease (Glomerulonephritis) or kidney and lung disease (Goodpasture syndrome). Such symptoms may include:
    • Kidney failure
    • Respiratory failure
    • Chest pain
    • Chills and fever
    • Weight loss
    • Hematuria
    • Vomiting
    • Pulmonary haemorrhage (coughing up blood)
    • Anaemia due to bleeding.
    • How is the sample collected?

      Venous blood is collected from a vein in the arm.

      How to prepare for the test?

      No special preparations are required for this test.

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      Anti-GBM Antibody (IF Method) Test availability by city

      Pricing and home collection availability may vary by city. Select your location to view the current booking options.

      Hyderabad

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      Delhi

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      Mumbai

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      Bengaluru

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      Chennai

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      What our patients say

      “Simple home collection process and helpful staff.”

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      “The booking experience was convenient and the report was easy to access.”

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      “Professional sample collection with timely updates.”

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      Frequently asked questions

      This test helps assess relevant health markers. Your doctor can interpret the result together with symptoms, history and other investigations.

      Preparation requirements can vary. Follow the instructions shown during booking or those provided by your doctor or Apollo Diagnostics.

      Home sample collection is available in supported locations. Availability is confirmed during booking based on your selected city and address.

      Reports are made available digitally after laboratory processing is complete. Report time can vary by test and location.

      A healthcare professional should interpret results that are abnormal, unexpected or associated with symptoms.

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