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E2A(19P13) AND PBX1(1Q23) - T(1;19)(Q23;P13) - ALL
The common chromosome translocations in pediatric ALL include t(1;19) (q23 ;p13.3); TCF3-PBX1(E2A- PBX1), t(12; 21) (p13;q22); ETV6-RUNX1(TEL-AML1) & MLL gene rearrangement. The chromosome anomaly is associated with adverse prognostic features.
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