Angiotensin Converting Enzyme(ACE)

The angiotensin Converting Enzyme (ACE) is an enzyme that converts Angiotensin I to Angiotensin II. Angiotensin II is an active vasoconstrictor that constricts blood vessels and increases blood pressure. Angiotensin converting enzyme test is a simple blood test that measures the levels of angiotensin in the blood. The test is usually ordered to diagnose sarcoidosis – a systemic granulomatous disease that mostly affects the lungs.

Why is the test performed?

The test is useful for confirming the presence of sarcoidosis and is also helpful in the diagnosis and monitoring of the disease. The test may also be helpful in confirming Gaucher disease and leprosy.

When is the test ordered?

The test may be recommended if an individual has signs and symptoms suggestive of sarcoidosis, which include:

Shortness of breath

Chronic cough

Great

Red eyes

Joint pain

The test may also be ordered for individuals undergoing treatment for Sarcoidosis to gauge the progress of the disease and to monitor the efficiency of the treatment in controlling the disease.

How is the sample collected?

A blood sample is collected from a vein in the arm.

How to prepare for the test?

Prior to undergoing the ACE test, a physician might instruct the patient to restrain from eating and drinking for up to 12 hours before the test. Also, if the person is on steroid medication, it is better to ask the physician whether they should be stopped.

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