Quadruple Marker Screening 2nd Trimester

The Quadruple Marker Screening test provides some critical information about a pregnancy – for instance, the likelihood of an inherited or genetic disorder occurring in the baby growing inside a pregnant woman. Yet, it is a presumptive and not a confirmatory test for the diagnosis of a specific disorder.

The quad test is useful for predicting developmental disorders in a baby, such as Down syndrome and neural tube defects. The test measures: Human Chorionic Gonadotropin (hCG), Inhibin-A, UE-Unconjugated Estriol, and Alpha-feto protein.

Why is the test done?

The test is a screening test, which may be prescribed to assess the risk of certain birth defects, such as neural tube defects and Down syndrome in a baby.Women who have conceived at an older age (35 plus age), with a strong family history of

birth defects or on insulin therapy may be at an increased risk of giving birth to a baby with birth defects.

When is the test recommended?

Quadruple Marker screening test may be recommended during 15 and 20 weeks of pregnancy.

How is the sample collected?

A blood sample is drawn from a vein in the arm.

How to prepare for the test?

No special preparation is required for the test.

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