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Triple Marker Screening 2nd Trimester

The Triple Marker Screening test provides critical information about a pregnancy – for instance, the likelihood of an inherited or genetic disorder occurring in the baby growing inside a pregnant woman. Yet, it is a presumptive and not a confirmatory test for the diagnosis of a specific disorder.


The Triple marker test is useful for predicting developmental disorders in a baby, such as Spina Bifida, neural tube defects & anencephaly .The test measures: Human Chorionic Gonadotropin (hCG), Alpha-feto protein, Estriol. An alternative to this test is the quadruple marker screen test, which also looks at a substance called inhibin A.

Why is the test done?

The test is a screening test, which may be prescribed to assess the risk of certain birth defects, such as Spina Bifida, neural tube defects and anencephaly. This test can also indicate a molar pregnancy, or a multiple pregnancy with two or more children.

When is the test recommended?

Triple Marker screening test may be recommended during 15 and 20 weeks of pregnancy. The test is often most recommended for women with 35 years old or older, having a family history of birth defects.

How is the sample collected?

A blood sample is drawn from a vein in the arm.

How to prepare for the test?

No special preparation is required for the test.

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